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    • 提纯(extract)血浆中cfDNA的磁珠
    • 选择(select)特定范围DNA片段的磁珠
    • 捕获(capture)特定序列DNA片段的磁珠
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选择特定范围DNA片段的磁珠

产品名称 应用 目录号 规格/价格(1ml, USD) 加入购物车
MagVigen™ – Easy DNA Size Selection 试剂盒 Magnetic nanobeads for ratio based DNA size 100~500bp. Perfect XP alternative (same features & protocol).
Product Sheet
K61001-Easy-
MagVigen™ – Extended DNA Size Selection 试剂盒 Magnetic nanobeads for ratio based DNA size 100~500bp & 500~3000bp.
Product Sheet
K61001-Extend-
MagVigen™ – 500bp Focus, DNA Selection 试剂盒 Including MagVigen™ magnetic nanobeads, DNA fragment size selection of 500bp Capture Buffers, Elution Buffer
Product Sheet
Kf61001-500 Focus $339 PayPal

希望先试用一下 MagVigen™?
申请测试用样本

DNA Size Selection and DNA Clean-up for NGS DNA Library Purification产品介绍: MagVigen™ DNA Select磁性纳米颗粒是为DNA纯化量身定制的,能高效快速地将>100bp, >200bp, >300bp, >400bp, >500bp,>700bp, >1000 bp, >1500bp的DNA从样本中分离纯化出来。目标DNA 可以是单链也可以是双链。实验过程大致可分为三步。首先,MagVigen™ DNA Select磁性纳米颗粒与实验样本进行短暂的(约10min)共孵育,以捕获样本中特定片段长度范围的目标DNA。然后,用磁铁将生成的纳米颗粒-DNA片段复合物与样品中的其他组分分离开来。最后,洗脱纳米颗粒-DNA片段复合物,得到目标DNA。

下游应用: 下一代测序,PCR定量,凝胶电泳等

产品特点:

  • 可选择体积比或序列特异性DNA分离
  • 长片段DNA分离技术
  • DNA长度分离范围精确
  • 高产量
  • 分离简单迅速
  • 快速磁响应
  • 可靠性重复性强
  • 寡核苷酸缀合磁珠可用于耐热,pH值稳定的核酸提取

实验例子:

magvigen-dna-precise-size-selection-by-adjusting-volume-ratio

Figure 1. 1000ng Fisher DNA ladder was size-specifically captured by MagVigen™ nanobeads by adjusting the ratios of MagVigen™ volume vs. DNA sample volume. The numbers on top indicate the ratio.

magvigen-long-bp-selection (700bp)

Figure 2. DNA sizing results by adjusting the ratios of MagVigen™ beads volume vs. DNA sample volume to obtain long DNA sizes (up to 1000bp). The top number indicating beads volume vs. DNA volume.

纯化前 纯化后

strong contamination DNA library before purification (adapter dimer ratio 224%)

after DNA sizing purification with AmPure XP (dimer ratio > 6%)

after DNA sizing purification with MagVigen (dimer ratio <3%)

Figure 3. MagVigen™ Easy DNA Size Selection Kit (K61001-Easy) outperforms conventional brand products for strongly contanminated NGS DNA Library sample (adapter dimer ratio 224%). After clean-up, adapter dimer over library is less than 3% using MagVigen™ (passes quality control (QC)) vs. more than 6% using AmPure XP (fails QC).

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