Products

Product Lines of NVIGEN’s Nanopbeads Technology:

MagVigen™ | Magnetic nanoparticles (nanobeads) for DNA capture and purification, immunoprecipitation, molecular and cellular purification and identification.
MyQuVigen™ | Combination of magnetic nanoparticles and quantum dots for imaging, manipulation and detection.
MaxVigen™ | Multifunctional nanobeads for in vivo targeted delivery and imaging.
AuVigen™ | Bio-compatible gold nanoparticles for biological sensing, imaging and therapeutic applications.

Applications:

Product name	Cat#	DNA capture, sizing, cleanup	cfDNA extraction	Sequence specific DNA Capture	mRNA capture	Cell separation	Protein purifi-cation	Immuno-assay	CAR‑T	OrderNow
MagVigen cfDNA Extraction Kit	K61003		v
MagVigen EASY DNA Select Kit	K61001-Easy	v
MagVigen Extended Long Reads DNA Select Kit	K61001-Extend	v
MagVigen Streptavidin DNA Capture Kit	K61002	v		v	v
MagVigen-Poly T mRNA Select Kit	K61004				v
MagVigen FFPE DNA Extraction Kit	K61007	v
MagVigen Oligo Conjugation Kit	K61008	v		v	v
MagVigen anti-EpCAM, Human Kit	K51001					v
MagVigen anti-CD45, Human Kit	K51002					v
MagVigen Streptaviden Kit, Cell Separation	K21005C					v
MagVigen Protein A, Kit	K21003						v	v
MagVigen Protein G, Kit	K21004						v	v
MagVigen Streptaviden Kit, Protein Capture	K21005P						v	v
MagVigen anti-Rabbit IgG	K21006						v	v
MagVigen anti-Mouse IgG	K21007						v	v
MagVigen T cell Activation Kit, Human	51200								v

NVIGEN designs and engineers our nanoparticles (nanobeads) and surface conjugations. Our ready-to-use nanoparticle reagents are compatible and ideal for experimental workflows, molecular imaging, IVD and therapeutics. We also offer services that can customize nanoparticles with specific surface functional groups to bind specific ligands.

Our most popular products for DNA size selection, DNA capture, Cell free DNA Extraction, and protein co-immunoprecipitation come from our MagVigen™ platform. MagVigen™ nanoparticles have strong magnetism, sensitivity and binding specificity. We are able to customize and fine-tune surface conjugation and particle functionalities, making MagVigen™ ideal for use in a wide variety or applications. Magnetic separation is fast yet gentle, causing minimal disruption to your target proteins, permitting the isolation and preservation of labile compositions and conformations that might otherwise being interfered. See below for more in-depth descriptions of our magnetic beads and how they can assist you in your research.

MagVigen™

Magnetic nanoparticles with high magnetic response and binding specificity.

MagVigen™ magnetic nanoparticles easily respond to an external magnet. MagVigen™ is one of our top selling magnetic bead products a which has maximum versatility in its usages.

Advantages of MagVigen™ magnetic nanoparticles:

Magnetic separation is simple and fast. No columns or centrifugation needed.
No residual magnetism when magnetic field is removed.
Nano-size beads minimize interference within interacting complexes.
High recovery rate and performance consistency.
High capacity and elution efficiency.
Enable novel biomarker identification.
Economical.

Applications of MagVigen™ magnetic nanoparticles:

Protein-antibody purification
Immunoprecipitation
Chromatin immunoprecipitation
DNA and RNA purification
Cell separation and enrichment
Molecular enrichment

Three easy steps using MagVigen™ - protein A nanoparticles for protein enrichment and purification:

Mix: Mix MagVigen™ nanoparticles with DNA/RNA sample.
Bind: When mixed with a sample, MagVigen™ nanoparticles bind to the desired target (i.e. cells, pathogenic microorganisms, nucleic acids, peptides, proteins or protein complexes, etc). This interaction relies on the specific affinity of the ligand conjugated to the surface of the nanoparticles. NVIGEN engineers the surface conjugations you desire.
Wash: The beads respond to a magnetic force (by use of a magnet), allowing bound material to be rapidly and efficiently separated from the rest of the sample. After unbound materials are removed by aspiration, the nanoparticle-bound targets are washed by using the magnet.
Elute: The bound target is released from the nanoparticles and can be used for downstream applications.

MyQuVigen™

A unique combination of magnetic and fluorescent properties into one functional nanoparticles bead.

Isolation and concurrent staining of human cancer cells with green or red fluorescence MyQuVigen™ - streptavidin nanoparticles.

Advantages of MyQuVigen™ fluorescent magnetic nanoparticles:

Concurrent magnetic separation and fluorescent labeling.
High magnetic response
Bright stable fluorescence
Superior multiplexing capability
Perfect for molecular and cellular imaging and detection

Applications of MyQuVigen™ fluorescent mangetic nanoparticles:

Multiplexed diagnostic assays
High sensitivity biodetection
Magnetic actuation
Cellular separation and imaging

MaxVigen™

Multifunctional nanobeads for in vivo imaging, targeting and drug delivery applications.

Tumor neovasculature imaged using MaxVigen™ NIR fluorescence.

Advantages of MaxVigen™ multifunctional nanoparticles:

Superior detection sensitivity through fluorescence and/or MRI
Highly enhanced permeability and retention effect
35 Days of cancer region observation window, 600% increase compared to other commercial products.

Applications of MaxVigen™ multifunctional nanoparticles:

Vasculature/cancer/inflammation imaging
Molecular imaging and targeting
Multimodality fluorescence and magnetic resonance imaging
Combined molecular imaging and drug delivery
In vitro and in vivo imaging of molecular interactions

AuVigen™

Gold nanoparticles with superior biocompatibility.

Nanoparticle stability evaluated with increased salt concentration. Other commercial Au nanoparticles have much less salt tolerance, indicated by the purple color formed by nanoparticles aggregation.

Advantages of AuVigen™ gold nanoparticles:

Distinct surface plasmon features
Stable and tailorable surfaces
Tunable sizes
Multiplexing based on SPR property
Suitable as injectable reagents for in vivo imaging and therapeutic research

Applications of AuVigen™ gold nanoparticles:

Immuno staining and detection
Protein crystallography tag
SERS substrate
Making Bio-conjugates of Au nanoparticles with DNA, RNA or proteins
In vitro molecular imaging, drug delivery or photo thermal therapy